Generation of single cell identity by homophilic interactions between combinations of α, β and γ protocadherins

Individual mammalian neurons express distinct repertoires of protocadherin (Pcdh) -α, -β and -γ proteins that function in neural circuit assembly. Here we show that all three types of Pcdhs can engage in specific homophilic interactions, that cell surface delivery of alternate Pcdhα isoforms require...

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Main Authors: Thu, Chan Aye, Chen, Weisheng V., Rubinstein, Rotem, Chevee, Maxime, Wolcott, Holly N, Felsovalyi, Klara O, Tapia, Juan Carlos, Shapiro, Lawrence, Honig, Barry, Maniatis, Tom
Formato: Artigo
Idioma:Inglês
Publicado: 2014
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4183217/
https://ncbi.nlm.nih.gov/pubmed/25171406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2014.07.012
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