Generation of single cell identity by homophilic interactions between combinations of α, β and γ protocadherins

Individual mammalian neurons express distinct repertoires of protocadherin (Pcdh) -α, -β and -γ proteins that function in neural circuit assembly. Here we show that all three types of Pcdhs can engage in specific homophilic interactions, that cell surface delivery of alternate Pcdhα isoforms require...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Thu, Chan Aye, Chen, Weisheng V., Rubinstein, Rotem, Chevee, Maxime, Wolcott, Holly N, Felsovalyi, Klara O, Tapia, Juan Carlos, Shapiro, Lawrence, Honig, Barry, Maniatis, Tom
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2014
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4183217/
https://ncbi.nlm.nih.gov/pubmed/25171406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2014.07.012
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