γ-Protocadherin structural diversity and functional implications

Stochastic cell-surface expression of α-, β-, and γ-clustered protocadherins (Pcdhs) provides vertebrate neurons with single-cell identities that underlie neuronal self-recognition. Here we report crystal structures of ectodomain fragments comprising cell-cell recognition regions of mouse γ-Pcdhs γA...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Goodman, Kerry Marie, Rubinstein, Rotem, Thu, Chan Aye, Mannepalli, Seetha, Bahna, Fabiana, Ahlsén, Göran, Rittenhouse, Chelsea, Maniatis, Tom, Honig, Barry, Shapiro, Lawrence
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2016
Assuntos:
Biophysics and Structural Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5106212/
https://ncbi.nlm.nih.gov/pubmed/27782885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.20930
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