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γ-Protocadherin structural diversity and functional implications
Stochastic cell-surface expression of α-, β-, and γ-clustered protocadherins (Pcdhs) provides vertebrate neurons with single-cell identities that underlie neuronal self-recognition. Here we report crystal structures of ectodomain fragments comprising cell-cell recognition regions of mouse γ-Pcdhs γA...
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Publié dans: | eLife |
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Auteurs principaux: | , , , , , , , , , |
Format: | Artigo |
Langue: | Inglês |
Publié: |
eLife Sciences Publications, Ltd
2016
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Sujets: | |
Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5106212/ https://ncbi.nlm.nih.gov/pubmed/27782885 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.20930 |
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