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Probing the stochastic, motor-driven properties of the cytoplasm using force spectrum microscopy

Molecular motors in cells typically produce highly directed motion; however, the aggregate, incoherent effect of all active processes also creates randomly fluctuating forces, which drive diffusive-like, non-thermal motion. Here we introduce force-spectrum-microscopy (FSM) to directly quantify rando...

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Detalhes bibliográficos
Main Authors: Guo, Ming, Ehrlicher, Allen J., Jensen, Mikkel H., Renz, Malte, Moore, Jeffrey R., Goldman, Robert D., Lippincott-Schwartz, Jennifer, Mackintosh, Frederick C., Weitz, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4183065/
https://ncbi.nlm.nih.gov/pubmed/25126787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2014.06.051
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