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Discovery and Labeling of High Affinity 3,4-Diarylpyrazolines as Candidate Radioligands for In Vivo Imaging of Cannabinoid Subtype-1 (CB(1)) Receptors

Imaging of cannabinoid subtype-1 (CB(1)) receptors in vivo with positron emission tomography (PET) is likely to be important for understanding their role in neuropsychiatric disorders and for drug development. Radioligands for imaging with PET are required for this purpose. We synthesized new ligand...

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Main Authors: Donohue, Sean R., Pike, Victor W., Finnema, Sjoerd J., Truong, Phong, Andersson, Jan, Gulyás, Balázs, Halldin, Christer
Formato: Artigo
Idioma:Inglês
Publicado: 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4182912/
https://ncbi.nlm.nih.gov/pubmed/18754613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm800329z
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