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Reduced Methylprednisolone Clearance Causing Prolonged Pharmacodynamics in a Healthy Subject Was Not Associated With CYP3A5*3 Allele or a Change in Diet Composition

The influence of diet and genetics was investigated in a healthy white person who had distinctly low methylprednisolone clearance. Pharmacokinetic and pharmacodynamic parameter values were similar on 2 occasions during the consumption of a low-carbohydrate diet and a Weight Watchers diet, indicating...

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書誌詳細
主要な著者: Lee, Su-Jun, Jusko, William J., Salaita, Christine G., Calis, Karim A., Jann, Michael W., Spratlin, Vicky E., Goldstein, Joyce A., Hon, Yuen Yi
フォーマット: Artigo
言語:Inglês
出版事項: 2006
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4182867/
https://ncbi.nlm.nih.gov/pubmed/16638735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0091270006287588
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