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Altered Methylprednisolone Pharmacodynamics in Healthy Subjects With Histamine N-Methyltransferase C314T Genetic Polymorphism

This study investigated the potential differences in methylprednisolone pharmacodynamics between healthy subjects with different histamine N-methyltransferase (HNMT) C314T genotypes. Six individuals with C/C genotype and 4 with C/T genotype were administered a single intravenous dose of methylpredni...

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Detalhes bibliográficos
Main Authors: Hon, Yuen Yi, Jusko, William J., Spratlin, Vicky E., Jann, Michael W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4196422/
https://ncbi.nlm.nih.gov/pubmed/16554448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0091270006286434
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