Calcium-Activated Potassium Current Modulates Ventricular Repolarization in Chronic Heart Failure

The role of I(KCa) in cardiac repolarization remains controversial and varies across species. The relevance of the current as a therapeutic target is therefore undefined. We examined the cellular electrophysiologic effects of I(KCa) blockade in controls, chronic heart failure (HF) and HF with sustai...

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Main Authors: Bonilla, Ingrid M., Long, Victor P., Vargas-Pinto, Pedro, Wright, Patrick, Belevych, Andriy, Lou, Qing, Mowrey, Kent, Yoo, Jae, Binkley, Philip F., Fedorov, Vadim V., Györke, Sandor, Janssen, Paulus M. L., Kilic, Ahmet, Mohler, Peter J., Carnes, Cynthia A.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2014
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4182742/
https://ncbi.nlm.nih.gov/pubmed/25271970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0108824
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