Activation of Liver X Receptors inhibits of Hedgehog signaling, clonogenic growth, and self-renewal in multiple myeloma

The Hedgehog (Hh) signaling pathway is aberrantly activated in a wide variety of human cancers, and recent clinical studies have demonstrated that pathway inhibitors are effective in advanced basal cell carcinoma (BCC). The majority of these agents have been designed to target SMOOTHENED (SMO), a tr...

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Bibliografski detalji
Glavni autori: Agarwal, Jasmin R., Wang, Qiuju, Tanno, Toshihiko, Rasheed, Zeshaan, Merchant, Akil, Ghosh, Nilanjan, Borrello, Ivan, Huff, Carol Ann, Parhami, Farhad, Matsui, William
Format: Artigo
Jezik:Inglês
Izdano: 2014
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4182725/
https://ncbi.nlm.nih.gov/pubmed/24807964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-13-0997
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