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Biological and Molecular Effects of Small Molecule Kinase Inhibitors on Low-Passage Human Colorectal Cancer Cell Lines

Low-passage cancer cell lines are versatile tools to study tumor cell biology. Here, we have employed four such cell lines, established from primary tumors of colorectal cancer (CRC) patients, to evaluate effects of the small molecule kinase inhibitors (SMI) vemurafenib, trametinib, perifosine, and...

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Autors principals: Lange, Falko, Franz, Benjamin, Maletzki, Claudia, Linnebacher, Michael, Hühns, Maja, Jaster, Robert
Format: Artigo
Idioma:Inglês
Publicat: Hindawi Publishing Corporation 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4182691/
https://ncbi.nlm.nih.gov/pubmed/25309914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/568693
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