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Biological and Molecular Effects of Small Molecule Kinase Inhibitors on Low-Passage Human Colorectal Cancer Cell Lines

Low-passage cancer cell lines are versatile tools to study tumor cell biology. Here, we have employed four such cell lines, established from primary tumors of colorectal cancer (CRC) patients, to evaluate effects of the small molecule kinase inhibitors (SMI) vemurafenib, trametinib, perifosine, and...

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Detalhes bibliográficos
Main Authors: Lange, Falko, Franz, Benjamin, Maletzki, Claudia, Linnebacher, Michael, Hühns, Maja, Jaster, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4182691/
https://ncbi.nlm.nih.gov/pubmed/25309914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/568693
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