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Sodium-Glucose Transporter-2 (SGLT2; SLC5A2) Enhances Cellular Uptake of Aminoglycosides

Aminoglycoside antibiotics, like gentamicin, continue to be clinically essential worldwide to treat life-threatening bacterial infections. Yet, the ototoxic and nephrotoxic side-effects of these drugs remain serious complications. A major site of gentamicin uptake and toxicity resides within kidney...

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Detalhes bibliográficos
Main Authors: Jiang, Meiyan, Wang, Qi, Karasawa, Takatoshi, Koo, Ja-Won, Li, Hongzhe, Steyger, Peter S.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4182564/
https://ncbi.nlm.nih.gov/pubmed/25268124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0108941
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