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TRPV4 enhances cellular uptake of aminoglycoside antibiotics
The cochlea and kidney are susceptible to aminoglycoside-induced toxicity. The non-selective cation channel TRPV4 is expressed in kidney distal tubule cells, and hair cells and the stria vascularis in the inner ear. To determine if TRPV4 is involved in aminoglycoside trafficking, we developed a muri...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2008
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2736053/ https://ncbi.nlm.nih.gov/pubmed/18682499 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.023705 |
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