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A Simple Extension to the CMASA Method for the Prediction of Catalytic Residues in the Presence of Single Point Mutations

The automatic identification of catalytic residues still remains an important challenge in structural bioinformatics. Sequence-based methods are good alternatives when the query shares a high percentage of identity with a well-annotated enzyme. However, when the homology is not apparent, which occur...

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Autori principali: Flores, David I., Sotelo-Mundo, Rogerio R., Brizuela, Carlos A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4182483/
https://ncbi.nlm.nih.gov/pubmed/25268770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0108513
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