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Adjuvant Potential of Selegiline in Attenuating Organ Dysfunction in Septic Rats with Peritonitis
Selegiline, an anti-Parkinson drug, has antioxidant and anti-apoptotic effects. To explore the effect of selegiline on sepsis, we used a clinically relevant animal model of polymicrobial sepsis. Cecal ligation and puncture (CLP) or sham operation was performed in male rats under anesthesia. Three ho...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Public Library of Science
2014
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4182482/ https://ncbi.nlm.nih.gov/pubmed/25268350 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0108455 |
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