Therapeutic Effects of Procainamide on Endotoxin-Induced Rhabdomyolysis in Rats

Overt systemic inflammatory response is a predisposing mechanism for infection-induced skeletal muscle damage and rhabdomyolysis. Aberrant DNA methylation plays a crucial role in the pathophysiology of excessive inflammatory response. The antiarrhythmic drug procainamide is a non-nucleoside inhibito...

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Bibliographic Details
Published in:PLoS One
Main Authors: Shih, Chih-Chin, Hii, Hiong-Ping, Tsao, Cheng-Ming, Chen, Shiu-Jen, Ka, Shuk-Man, Liao, Mei-Hui, Wu, Chin-Chen
Format: Artigo
Language:Inglês
Published: Public Library of Science 2016
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4769298/
https://ncbi.nlm.nih.gov/pubmed/26918767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0150319
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