Procainamide Inhibits DNA Methylation and Alleviates Multiple Organ Dysfunction in Rats with Endotoxic Shock

Excessive inflammatory and oxidative stress lead to circulatory failure, multiple organ dysfunction, and high mortality in patients with sepsis. Microbial infection-induced DNA hypermethylation is associated with the augmentation of inflammation and oxidative stress. In our previous study, the antia...

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Vydáno v:PLoS One
Hlavní autoři: Shih, Chih-Chin, Liao, Mei-Hui, Hsiao, Tsan-Seng, Hii, Hiong-Ping, Shen, Ching-Hui, Chen, Shiu-Jen, Ka, Shuk-Man, Chang, Yung-Lung, Wu, Chin-Chen
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2016
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5035080/
https://ncbi.nlm.nih.gov/pubmed/27661616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0163690
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