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Antimicrobial Distribution From Local Delivery Depends on Dose: A Pilot Study With MRI

BACKGROUND: Tissue distribution after local delivery has been quantified over a period of 5 hours on 7-T MRI in a rabbit model using gadolinium-labeled diethylenetriamine pentaacetic acid (Gd-DTPA) as an antimicrobial surrogate; however, it is unknown how the Gd-DTPA load in a local depot will affec...

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Detalhes bibliográficos
Main Authors: McLaren, Alex, Giers, Morgan B., Fraser, James, Hosack, Luke, Caplan, Michael R., McLemore, Ryan
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4182417/
https://ncbi.nlm.nih.gov/pubmed/24510357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11999-014-3493-1
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