Regulation of the Mitogen Activated Protein Kinase Kinase (MEK)-1 by NAD(+)-Dependent Deacetylases

Sirtuins are class III deacetylases that regulate many essential processes, including cellular stress, genome stability, and metabolism. Although these NAD(+)-dependent deacetylases control adaptive cellular responses, identification of sirtuin-regulated signaling targets remain under-studied. Here,...

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Main Authors: Yeung, Fan, Ramsey, Catherine S., Popko-Scibor, Anita E., Allison, David F., Gray, Lisa G., Shin, Min, Kumar, Manish, Li, Duo, McCubrey, James A., Mayo, Marty W.
格式: Artigo
語言:Inglês
出版: 2014
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4182313/
https://ncbi.nlm.nih.gov/pubmed/24681949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2014.39
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