Clinical significance of UGT1A1 gene polymorphisms on irinotecan-based regimens as the treatment in metastatic colorectal cancer

PURPOSE: The primary aim of this research was to investigate the association between uridine diphosphate glucuronosyltransferase (UGT)1A1 gene polymorphisms and the toxicities of irinotecan-based regimens in Chinese patients with metastatic colorectal cancer. METHODS: The study analyzed the distribu...

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Detalhes bibliográficos
Main Authors: Li, Minmin, Wang, Zhehai, Guo, Jun, Liu, Jie, Li, Changzheng, Liu, Lin, Shi, Huan, Liu, Liyan, Li, Huihui, Xie, Chao, Zhang, Xia, Sun, Wenwen, Fang, Shu, Bi, Xiang
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2014
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4181635/
https://ncbi.nlm.nih.gov/pubmed/25285015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S67867
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