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A genetic instrument for Mendelian randomization of fibrinogen

Mendelian randomization studies on fibrinogen commonly use a single genetic variant as an instrument, but this may explain only a small proportion of the total phenotypic variance. We examined the contribution of multiple common single nucleotide polymorphisms (SNPs) and haplotypes in the entire fib...

詳細記述

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書誌詳細
主要な著者: Ken-Dror, Gie, Humphries, Steve E., Kumari, Meena, Kivimaki, Mika, Drenos, Fotios
フォーマット: Artigo
言語:Inglês
出版事項: 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4181528/
https://ncbi.nlm.nih.gov/pubmed/22388766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10654-012-9666-x
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