Haplotype and genotype effects of the F7 gene on circulating factor VII, coagulation activation markers and incident coronary heart disease in UK men

BACKGROUND: Evidence for the associations of single nucleotide polymorphisms (SNPs) in the F7 gene and factor VII (FVII) levels and with risk of coronary heart disease (CHD) is inconsistent. We examined whether F7 tagging SNPs and haplotypes were associated with FVII levels, coagulation activation m...

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Hlavní autoři: Ken-Dror, Gie, Drenos, Fotios, Humphries, Steve E, Talmud, Philippa J, Hingorani, Aroon D, Kivimäki, Mika, Kumari, Meena, Bauer, Kenneth A, Morrissey, James H, Ireland, Helen A
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3226948/
https://ncbi.nlm.nih.gov/pubmed/20735728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1538-7836.2010.04035.x
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