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Evaluation of Genetic Markers as Instruments for Mendelian Randomization Studies on Vitamin D

BACKGROUND: Mendelian randomization (MR) studies use genetic variants mimicking the influence of a modifiable exposure to assess and quantify a causal association with an outcome, with an aim to avoid problems with confounding and reverse causality affecting other types of observational studies. AIM...

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Detalhes bibliográficos
Main Authors: Berry, Diane J., Vimaleswaran, Karani S., Whittaker, John C., Hingorani, Aroon D., Hyppönen, Elina
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3357436/
https://ncbi.nlm.nih.gov/pubmed/22629401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0037465
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