TGF-β signaling mediates endothelial to mesenchymal transition (EndMT) during vein graft remodeling

Veins grafted into an arterial environment undergo a complex vascular remodeling process. Pathologic vascular remodeling often results in stenosed or occluded conduit grafts. Understanding this complex process is important for improving the outcome of patients with coronary and peripheral artery dis...

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Main Authors: Cooley, Brian C., Nevado, Jose, Mellad, Jason, Yang, Dan, Hilaire, Cynthia St., Negro, Alejandra, Fang, Fang, Chen, Guibin, San, Hong, Walts, Avram D., Schwartzbeck, Robin L., Taylor, Brandi, Lanzer, Jan D., Wragg, Andrew, Elagha, Abdalla, Beltran, Leilani E., Berry, Colin, Feil, Robert, Virmani, Renu, Ladich, Elena, Kovacic, Jason C., Boehm, Manfred
Format: Artigo
Language:Inglês
Published: 2014
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4181409/
https://ncbi.nlm.nih.gov/pubmed/24622514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3006927
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