VEGFR1/ CXCR4 positive progenitor cells modulate local inflammation and augment tissue perfusion by a SDF-1 dependent mechanism

Recruitment and retention of circulating progenitor cells at the site of injured or ischemic tissues facilitates adult neo-vascularization. We hypothesized that cell therapy could modulate local neo-vascularization through the VEGF/SDF-1 axis and by paracrine effects on local endothelial cells. We i...

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Bibliografische gegevens
Hoofdauteurs: Wragg, Andrew, Mellad, Jason A, Beltran, Leilani E, Konoplyannikov, Mikhail, San, Hong, Boozer, Sherry, Deans, Robert J., Mathur, Anthony, Lederman, Robert J, Kovacic, Jason C, Boehm, Manfred
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2008
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2575081/
https://ncbi.nlm.nih.gov/pubmed/18690419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00109-008-0390-7
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