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Krüppel-like transcription factors KLF1 and KLF2 have unique and coordinate roles in regulating embryonic erythroid precursor maturation

The Krüppel-like transcription factors KLF1 and KLF2 are essential for embryonic erythropoiesis. They can partially compensate for each other during mouse development, and coordinately regulate numerous erythroid genes, including the β-like globins. Simultaneous ablation of KLF1 and KLF2 results in...

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Main Authors: Vinjamur, Divya S., Wade, Kristen J., Mohamad, Safa F., Haar, Jack L., Sawyer, Stephen T., Lloyd, Joyce A.
Format: Artigo
Jezik:Inglês
Izdano: Ferrata Storti Foundation 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4181252/
https://ncbi.nlm.nih.gov/pubmed/25150253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2014.104943
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