Krüppel-like Factor 2 Regulated Gene Expression in Mouse Embryonic Yolk Sac Erythroid Cells

KLF2 is a Krüppel-like zinc-finger transcription factor required for blood vessel, lung, T-cell and erythroid development. KLF2-/- mice die by embryonic day 14.5 (E14.5), due to hemorrhaging and heart failure. In KLF2-/- embryos, β-like globin gene expression is reduced, and E10.5 erythroid cells ex...

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Main Authors: Redmond, Latasha C., Dumur, Catherine I., Archer, Kellie J., Grayson, Dennis R., Haar, Jack L., Lloyd, Joyce A.
Formato: Artigo
Idioma:Inglês
Publicado: 2011
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3150518/
https://ncbi.nlm.nih.gov/pubmed/21530336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcmd.2011.03.002
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