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Establishing Ion Ratio Thresholds Based on Absolute Peak Area for Absolute Protein Quantification using Protein Cleavage Isotope Dilution Mass Spectrometry

Quantitative mass spectrometry has become central to the field of proteomics and metabolomics. Selected reaction monitoring is a widely used method for the absolute quantification of proteins and metabolites. This method renders high specificity using several product ions measured simultaneously. Wi...

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Detalhes bibliográficos
Main Authors: Loziuk, Philip L., Sederoff, Ronald R., Chiang, Vincent L., Muddiman, David C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4180812/
https://ncbi.nlm.nih.gov/pubmed/25154770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c4an00567h
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