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The effect of multistage nanovector targeting of VEGFR2 positive tumor endothelia on cell adhesion and local payload accumulation

Nanovectors are a viable solution to the formulation of poorly soluble anticancer drugs. Their bioaccumulation in the tumor parenchyma is mainly achieved exploiting the enhanced permeability and retention (EPR) effect of the leaky neovasculature. In this paper we demonstrate that multistage nanovect...

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Tallennettuna:
Bibliografiset tiedot
Päätekijät: Martinez, Jonathan O., Evangelopoulos, Michael, Karun, Vivek, Shegog, Evan, Wang, Joshua A., Boada, Christian, Liu, Xuewu, Ferrari, Mauro, Tasciotti, Ennio
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2014
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4180774/
https://ncbi.nlm.nih.gov/pubmed/25176066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2014.08.024
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