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The effect of multistage nanovector targeting of VEGFR2 positive tumor endothelia on cell adhesion and local payload accumulation

Nanovectors are a viable solution to the formulation of poorly soluble anticancer drugs. Their bioaccumulation in the tumor parenchyma is mainly achieved exploiting the enhanced permeability and retention (EPR) effect of the leaky neovasculature. In this paper we demonstrate that multistage nanovect...

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Autori principali: Martinez, Jonathan O., Evangelopoulos, Michael, Karun, Vivek, Shegog, Evan, Wang, Joshua A., Boada, Christian, Liu, Xuewu, Ferrari, Mauro, Tasciotti, Ennio
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4180774/
https://ncbi.nlm.nih.gov/pubmed/25176066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2014.08.024
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