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Thyroid hormone induction of human cholesterol 7 alpha-hydroxylase (Cyp7a1) in vitro
Thyroid hormone (TH) modulates serum cholesterol by acting on TH receptor β1 (TRβ1) in liver to regulate metabolic gene sets. In rodents, one important TH regulated step involves induction of Cyp7a1, an enzyme in the cytochrome P450 family, which enhances cholesterol to bile acid conversion and play...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4180720/ https://ncbi.nlm.nih.gov/pubmed/24582860 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mce.2014.02.003 |
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