Thyroid hormone induction of human cholesterol 7 alpha-hydroxylase (Cyp7a1) in vitro

Thyroid hormone (TH) modulates serum cholesterol by acting on TH receptor β1 (TRβ1) in liver to regulate metabolic gene sets. In rodents, one important TH regulated step involves induction of Cyp7a1, an enzyme in the cytochrome P450 family, which enhances cholesterol to bile acid conversion and play...

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Detaylı Bibliyografya
Asıl Yazarlar: Lammel Lindemann, Jan A., Angajala, Anusha, Engler, David A., Webb, Paul, Ayers, Stephen D.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2014
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Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4180720/
https://ncbi.nlm.nih.gov/pubmed/24582860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mce.2014.02.003
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