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Evolutionary Conservation and Expression of Human RNA-Binding Proteins and Their Role in Human Genetic Disease

RNA-binding proteins (RBPs) are effectors and regulators of posttranscriptional gene regulation (PTGR). RBPs regulate stability, maturation, and turnover of all RNAs, often binding thousands of targets at many sites. The importance of RBPs is underscored by their dysregulation or mutations causing a...

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Detalhes bibliográficos
Main Authors: Gerstberger, Stefanie, Hafner, Markus, Ascano, Manuel, Tuschl, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4180674/
https://ncbi.nlm.nih.gov/pubmed/25201102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-1221-6_1
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