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Evolutionary Conservation and Expression of Human RNA-Binding Proteins and Their Role in Human Genetic Disease
RNA-binding proteins (RBPs) are effectors and regulators of posttranscriptional gene regulation (PTGR). RBPs regulate stability, maturation, and turnover of all RNAs, often binding thousands of targets at many sites. The importance of RBPs is underscored by their dysregulation or mutations causing a...
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Главные авторы: | , , , |
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Формат: | Artigo |
Язык: | Inglês |
Опубликовано: |
2014
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Предметы: | |
Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4180674/ https://ncbi.nlm.nih.gov/pubmed/25201102 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-1221-6_1 |
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