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Leptin modulates autophagy in human CD4(+)CD25(−) conventional T cells
OBJECTIVE: In this report we show that the adipocytokine leptin directly modulates autophagy in human CD4(+)CD25(−) conventional (Tconv) T cells. RESULTS: In vitro treatment with recombinant human leptin determined an inhibition of autophagy during T cell receptor (TCR) stimulation, and this phenome...
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Hauptverfasser: | , , , , , , |
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Format: | Artigo |
Sprache: | Inglês |
Veröffentlicht: |
W.B. Saunders
2014
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Schlagworte: | |
Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4180014/ https://ncbi.nlm.nih.gov/pubmed/25060689 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.metabol.2014.06.010 |
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