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Leptin neutralization interferes with pathogenic T cell autoreactivity in autoimmune encephalomyelitis
Recent evidence has indicated that leptin, an adipocyte-secreted hormone belonging to the helical cytokine family, significantly influences immune and autoimmune responses. We investigate here the mechanisms by which in vivo abrogation of leptin effects protects SJL/J mice from proteolipid protein p...
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| Autori principali: | , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Clinical Investigation
2006
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1326145/ https://ncbi.nlm.nih.gov/pubmed/16410832 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI26523 |
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