Leptin neutralization interferes with pathogenic T cell autoreactivity in autoimmune encephalomyelitis

Recent evidence has indicated that leptin, an adipocyte-secreted hormone belonging to the helical cytokine family, significantly influences immune and autoimmune responses. We investigate here the mechanisms by which in vivo abrogation of leptin effects protects SJL/J mice from proteolipid protein p...

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Bibliografiset tiedot
Päätekijät: De Rosa, Veronica, Procaccini, Claudio, La Cava, Antonio, Chieffi, Paolo, Nicoletti, Giovanni Francesco, Fontana, Silvia, Zappacosta, Serafino, Matarese, Giuseppe
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Clinical Investigation 2006
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC1326145/
https://ncbi.nlm.nih.gov/pubmed/16410832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI26523
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