Leptin surge precedes onset of autoimmune encephalomyelitis and correlates with development of pathogenic T cell responses

In the work presented here, we explored the influence of leptin on the kinetics of experimental autoimmune encephalomyelitis (EAE) onset, in the EAE-associated inflammatory anorexia, and in the development of pathogenic T cell responses. We found that the expression of serum leptin increased before...

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Hauptverfasser: Sanna, Veronica, Di Giacomo, Antonio, La Cava, Antonio, Lechler, Robert I., Fontana, Silvia, Zappacosta, Serafino, Matarese, Giuseppe
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2003
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC151876/
https://ncbi.nlm.nih.gov/pubmed/12531880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200316721
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