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Interactions between Aβ oligomers and presynaptic cholinergic signaling: age-dependent effects on attentional capacities

Substantial evidence suggests that cerebral deposition of the neurotoxic fibrillar form of amyloid precursor protein, β-amyloid (Aβ), plays a critical role in the pathogenesis of Alzheimer's disease (AD). Yet, many aspects of AD pathology including the cognitive symptoms and selective vulnerabi...

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Detalhes bibliográficos
Main Authors: Parikh, Vinay, Bernard, Carcha S., Naughton, Sean X., Yegla, Brittney
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4179990/
https://ncbi.nlm.nih.gov/pubmed/25101540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbr.2014.07.046
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