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EFFECTS OF SUSTAINED PRONGF BLOCKADE ON ATTENTIONAL CAPACITIES IN AGED RATS WITH COMPROMISED CHOLINERGIC SYSTEM

Disruption in nerve growth factor (NGF) signaling via trkA receptors compromises the integrity of the basal forebrain (BF) cholinergic system, yielding cognitive, specifically attentional, impairments in Alzheimer’s disease (AD). Although normal aging is considered a risk factor for AD, the mechanis...

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Detalhes bibliográficos
Main Authors: YEGLA, BRITTNEY, PARIKH, VINAY
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3945974/
https://ncbi.nlm.nih.gov/pubmed/24374328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2013.12.042
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