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EFFECTS OF SUSTAINED PRONGF BLOCKADE ON ATTENTIONAL CAPACITIES IN AGED RATS WITH COMPROMISED CHOLINERGIC SYSTEM
Disruption in nerve growth factor (NGF) signaling via trkA receptors compromises the integrity of the basal forebrain (BF) cholinergic system, yielding cognitive, specifically attentional, impairments in Alzheimer’s disease (AD). Although normal aging is considered a risk factor for AD, the mechanis...
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2013
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Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3945974/ https://ncbi.nlm.nih.gov/pubmed/24374328 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2013.12.042 |
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