Načítá se...

Amyloid-β Oligomers Interact with Neurexin and Diminish Neurexin-mediated Excitatory Presynaptic Organization

Alzheimer’s disease (AD) is characterized by excessive production and deposition of amyloid-beta (Aβ) proteins as well as synapse dysfunction and loss. While soluble Aβ oligomers (AβOs) have deleterious effects on synapse function and reduce synapse number, the underlying molecular mechanisms are no...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Sci Rep
Hlavní autoři: Naito, Yusuke, Tanabe, Yuko, Lee, Alfred Kihoon, Hamel, Edith, Takahashi, Hideto
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5304201/
https://ncbi.nlm.nih.gov/pubmed/28211900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep42548
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!