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CRE promoter sites modulate alternative splicing via p300-mediated histone acetylation
Histone acetylation modulates alternative splicing of several hundred genes. Here, we tested the role of the histone acetyltransferase p300 in alternative splicing and showed that knockdown of p300 promotes inclusion of the fibronectin (FN1) alternative EDB exon. p300 associates with CRE sites in th...
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| Hoofdauteurs: | , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Landes Bioscience
2014
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4179961/ https://ncbi.nlm.nih.gov/pubmed/25019513 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/rna.29441 |
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