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Histone Deacetylase Activity Modulates Alternative Splicing
There is increasing evidence to suggest that splicing decisions are largely made when the nascent RNA is still associated with chromatin. Here we demonstrate that activity of histone deacetylases (HDACs) influences splice site selection. Using splicing-sensitive microarrays, we identified ∼700 genes...
Gorde:
| Egile Nagusiak: | , , , , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
Public Library of Science
2011
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3032741/ https://ncbi.nlm.nih.gov/pubmed/21311748 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0016727 |
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