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Total Synthesis of (±)-Cis-Trikentrin B via Intermolecular 6,7-Indole Aryne Cycloaddition and Stille Cross-Coupling

An efficient total synthesis of the annulated indole natural product (±)-cis-trikentrin B was accomplished by means of a regioselectively generated 6,7-indole aryne cycloaddition via selective metal-halogen exchange from a 5,6,7-tribromoindole. The unaffected C-5 bromine was subsequently used for a...

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Detalhes bibliográficos
Main Authors: Chandrasoma, Nalin, Brown, Neil, Brassfield, Allen, Nerurkar, Alok, Suarez, Susana, Buszek, Keith R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4179867/
https://ncbi.nlm.nih.gov/pubmed/25278636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetlet.2012.11.125
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