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New synthesis of (±)-cis-trikentrin A via tandem indole aryne cycloaddition/Negishi reaction. Applications to library development

We describe herein an efficient new route to the trikentrins and their related structures using a tandem 6,7-indolyne cycloaddition/Negishi cross-coupling reaction starting from a 4,6,7-tribromoindole (obtained in good yield via the Bartoli indole synthesis). The key step of this second generation r...

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Detalhes bibliográficos
Main Authors: Brown, Neil, Luo, Diheng, Decapo, Joseph A., Buszek, Keith R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2945378/
https://ncbi.nlm.nih.gov/pubmed/20877442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetlet.2009.09.083
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