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Ritonavir acts synergistically with panobinostat to enhance histone acetylation and inhibit renal cancer growth

There is currently no curative treatment for advanced renal cancer. Enhancing histone acetylation is a promising epigenetic-based therapy for cancer; however, in solid tumors, the efficacy of histone deacetylase (HDAC) inhibitors alone is limited. The human immunodeficiency virus protease inhibitor...

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Bibliografiske detaljer
Main Authors: SATO, AKINORI, ASANO, TAKAKO, ISONO, MAKOTO, ITO, KEIICHI, ASANO, TOMOHIKO
Format: Artigo
Sprog:Inglês
Udgivet: D.A. Spandidos 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4179797/
https://ncbi.nlm.nih.gov/pubmed/25279191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mco.2014.349
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