Aromatase Inhibitor-Associated Bone Fractures: A Case-Cohort GWAS and Functional Genomics

Bone fractures are a major consequence of osteoporosis. There is a direct relationship between serum estrogen concentrations and osteoporosis risk. Aromatase inhibitors (AIs) greatly decrease serum estrogen levels in postmenopausal women, and increased incidence of fractures is a side effect of AI t...

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Bibliografiske detaljer
Main Authors: Liu, Mohan, Goss, Paul E., Ingle, James N., Kubo, Michiaki, Furukawa, Yoichi, Batzler, Anthony, Jenkins, Gregory D., Carlson, Erin E., Nakamura, Yusuke, Schaid, Daniel J., Chapman, Judy-Anne W., Shepherd, Lois E., Ellis, Matthew J., Khosla, Sundeep, Wang, Liewei, Weinshilboum, Richard M.
Format: Artigo
Sprog:Inglês
Udgivet: Endocrine Society 2014
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4179631/
https://ncbi.nlm.nih.gov/pubmed/25148458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2014-1147
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