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Structure–activity analysis of a CFTR channel potentiator: Distinct molecular parts underlie dual gating effects

The cystic fibrosis (CF) transmembrane conductance regulator (CFTR) is a member of the ATP-binding cassette transporter superfamily that functions as an epithelial chloride channel. Gating of the CFTR ion conduction pore involves a conserved irreversible cyclic mechanism driven by ATP binding and hy...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Csanády, László, Töröcsik, Beáta
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: The Rockefeller University Press 2014
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4178936/
https://ncbi.nlm.nih.gov/pubmed/25267914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201411246
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