Plasmacytoid Dendritic Cells Mediate Synergistic Effects of HIV and Lipopolysaccharide on CD27(+) IgD(–) Memory B Cell Apoptosis

The effects of heightened microbial translocation on B cells during HIV infection are unknown. We examined the in vitro effects of HIV and lipopolysaccharide (LPS) on apoptosis of CD27(+) IgD(−) memory B (mB) cells from healthy controls. In vivo analysis was conducted on a cohort of 82 HIV(+) donors...

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Bibliografski detalji
Glavni autori: Zhang, Lumin, Luo, Zhenwu, Sieg, Scott F., Funderburg, Nicholas T., Yu, Xiaocong, Fu, Pingfu, Wu, Hao, Jiao, Yanmei, Gao, Yong, Greenspan, Neil S., Harding, Clifford V., Kilby, J. Michael, Li, Zihai, Lederman, Michael M., Jiang, Wei
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2014
Teme:
Pathogenesis and Immunity
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4178795/
https://ncbi.nlm.nih.gov/pubmed/25056888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00682-14
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