Plasmacytoid Dendritic Cells Mediate Synergistic Effects of HIV and Lipopolysaccharide on CD27(+) IgD(–) Memory B Cell Apoptosis

The effects of heightened microbial translocation on B cells during HIV infection are unknown. We examined the in vitro effects of HIV and lipopolysaccharide (LPS) on apoptosis of CD27(+) IgD(−) memory B (mB) cells from healthy controls. In vivo analysis was conducted on a cohort of 82 HIV(+) donors...

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Detalhes bibliográficos
Main Authors: Zhang, Lumin, Luo, Zhenwu, Sieg, Scott F., Funderburg, Nicholas T., Yu, Xiaocong, Fu, Pingfu, Wu, Hao, Jiao, Yanmei, Gao, Yong, Greenspan, Neil S., Harding, Clifford V., Kilby, J. Michael, Li, Zihai, Lederman, Michael M., Jiang, Wei
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4178795/
https://ncbi.nlm.nih.gov/pubmed/25056888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00682-14
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