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P2X-Selective Purinergic Antagonists Are Strong Inhibitors of HIV-1 Fusion during both Cell-to-Cell and Cell-Free Infection

Human immunodeficiency virus type 1 (HIV-1) infection is chronic and presently still incurable. Antiretroviral drugs effectively suppress replication; however, persistent activation of inflammatory pathways remains a key cause of morbidity. Recent studies proposed that purinergic signaling is requir...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Swartz, Talia H., Esposito, Anthony M., Durham, Natasha D., Hartmann, Boris M., Chen, Benjamin K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4178786/
https://ncbi.nlm.nih.gov/pubmed/25031337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01158-14
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